Erythema multiforme: case report and discussion.

نویسنده

  • L M Kroonen
چکیده

Erythema multiforme may be placed on a disease continuum that includes Stevens-Johnson syndrome and toxic epidermal necrolysis. It was first described in 1866 by Hebra as a skin disease with symmetrically distributed red papules, evolving within several days to form annular or iris-like shapes or blisters. The term multiforme described this evolution of primary lesions into different forms. In 1922 Stevens and Johnson described a febrile illness with stomatitis, purulent conjunctivitis, and skin lesions similar to those of erythema multiforme, which has become known as Stevens-Johnson syndrome or erythema multiforme major. l ,2 Toxic epidermal necrolysis, with severe exfoliation of the skin and mucous membranes and a high rate of mortality, is considered by many sources to be at the most severe extreme of this disease spectrum.

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عنوان ژورنال:
  • The Journal of the American Board of Family Practice

دوره 11 1  شماره 

صفحات  -

تاریخ انتشار 1998